Basic Information:
Product Name: Citrus Aurantium Extract
Latin Name: Citrus Aurantium L.
Part Used: Peel and Fruit
Active Ingredients:Synephrine，Synephrine Hydrochloride，Nobiletin and Tangeretin (Polymethoxylated Flavones, PMFs)
Appearance: Yellow-brown to off-white powder
Specifications:
Synephrine: 6%-95%
Synephrine Hydrochloride: 98%
Nobiletin + Tangeretin: 30%, 60%, 90%
CAS Number: 94-07-5
Molecular Formula: C9H13NO2
Molecular Weight: 167.21 g/mol
Additional Details:Mesh Size: 80 Mesh
Testing Method: High-Performance Liquid Chromatography (HPLC)
This extract, rich in bioactive compounds such as synephrine and PMFs, emerges as a light yellow to white powder.
Function:
Antioxidant Protection: Synephrine acts as a potent antioxidant, reducing the harmful effects of environmental pollutants on the body.
Connective Tissue Support: It helps consolidate connective tissues, thereby strengthening the skin, bones, teeth, and muscles.
Collagen Synthesis: Synephrine promotes the synthesis of collagen, aiding in faster wound healing.
Cholesterol Metabolism: It plays a role in cholesterol metabolism and assists in breaking down fats.
Nutrient Absorption: Synephrine enhances the absorption of iron and calcium, preventing conditions like scurvy.
Application:
Cardiovascular Health: Synephrine , especially from extracts like Hovenia dulcis and immature bitter orange, has notable effects on cardiovascular health. It can significantly improve myocardial contractility and pump function in anesthetized dogs while also strengthening the heart, constricting blood vessels, and enhancing arterial blood pressure. Modern studies have confirmed Synephrine 's ability to increase aortic tension and contract aortic smooth muscle in a concentration-dependent manner.
Weight Loss Aid: As a weight loss stimulant, synephrine (a compound often found in conjunction with Synephrine ) works by stimulating beta-3 adrenergic receptors, leading to lipid breakdown and thermogenesis. Dietary supplements containing synephrine typically also include ingredients like caffeine, salicylic acid, and ephedrine, enhancing synephrine’s weight loss effects.
Blood Pressure Regulation: In pharmacology, synephrine is used as a decongestant to treat hypotension when administered orally. It has significant effects on blood pressure, such as strengthening myocardial contractility, slowing the heart rate, increasing cardiac output, and enhancing coronary and renal blood flow.
Diabetes Management: Extracts from immature bitter orange, which include simferin, can boost the liver's antioxidant capacity and reduce liver cell damage.
Antidepressant Effects: P-synephrine has shown marked antidepressant effects in animal models with behavioral despair. It can mitigate depressive behaviors (such as prolonged immobility) by stimulating alpha-1 adrenergic receptors, potentially benefiting patients with depression accompanied by hypotension.
