043
NutriHerb
10-98% HPLC
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Basic Information:
Common Names: Diosmin
Specs:10-98%HPLC
Molecular Formula: C28H32O15
Molecular Weight: 608.54 g/mol
CAS Number: 520-27-4
Physical Properties:
Appearance: Light yellow to yellow crystalline powder
Melting Point: Approximately 270-272°C
Solubility: Slightly soluble in water; soluble in ethanol
Anti-Inflammatory and Allergy Resistance: Exhibits strong anti-inflammatory properties and helps reduce hypersensitivity reactions.
Antibacterial Properties: Effective against a range of bacteria and fungi, providing antimicrobial benefits.
Unique Physiological Functions: Compared to other plant flavonoids, orange flavonoids possess distinct physiological advantages.
Powerful Antioxidant: Protects against oxidative damage by neutralizing single oxygen atoms, peroxides, hydroxyl radicals, and other free radicals.
Cardiovascular Protection: Enhances the flexibility of capillaries, prevents platelet aggregation, and supports cardiovascular health by guarding the circulatory system against diseases.
Additional Benefits:
Potent Peroxynitrite Scavenger: Acts as a strong antioxidant against peroxynitrite.
Anti-Inflammatory Effects: Indirectly reduces inflammatory responses by inhibiting the release of arachidonic acid metabolites and histamine.
Prevents Blood Clot Formation: Inhibits platelet aggregation, thereby preventing thrombus formation and protecting the cardiovascular system. Also functions as a vasodilator, potentially beneficial in managing hypertension.
Lipid-Lowering Efficacy: Hesperetin and naringenin contribute to lowering lipid levels.
Antimutagenic Properties: Exhibits properties that may prevent genetic mutations.
Venous and Lymphatic Insufficiency: Diosmin is used to treat symptoms such as venous edema and soft tissue swelling associated with intravenous and lymphatic insufficiency.
Treatment of Vascular Disorders: Effective in addressing conditions like heavy limbs, numbness, pain, morning sickness, thrombophlebitis, and deep vein thrombosis.
Acute Hemorrhoid Relief: Diosmin can alleviate symptoms of acute hemorrhoids, including anal dampness, itching, bleeding, and pain.
ITEM | SPECIFICATION | RESULT |
Appearance | Greyish-yellow or light yellow, hygroscopic powder | Complies |
Solubility | Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in ethanol (96%), it dissolves in dilute solution of alkali hydroxides |
Complies |
Identification | A) IR: Complies diosmin CRS B) HPLC: Complies to the reference solution | Complies |
Iodine | ≤0.1% | Complies |
Related Substances | ||
Impurity A(Acetoisovanillone) | ≤1.0% | 0.03% |
Impurity B(Hesperidin) | ≤5.0% | 1.45% |
Impurity C(Isorhoifolin) | ≤3.0% | 2.02% |
Impurity E (Linarin) | ≤3.0% | 1.41% |
Impurity F(Diosmetin) | ≤3.0% | 0.74% |
Unspecified Impurities(each) | ≤1.0% | 0.35% |
Total Impurities | ≤10.0% | 6.16% |
Heavy Metals | ≤20ppm | Complies |
Water | ≤6.0% | 2.34% |
Sulphated Ash | ≤0.2% | 0.09% |
Particle Size | NLT95% pass 80 mesh | Complies |
Assay(HPLC, Anhydrous substance) | 90.0%~102.0% | 90.74% |
Residual Solvents | ||
Methanol | ≤3000ppm | Undetected |
Ethanol | ≤5000ppm | Undetected |
Pyridine | ≤200ppm | 94ppm |
Total Plate Count | ≤1000cfu/g | 50cfu/g |
-Yeast & Mold | ≤100cfu/g | <10cfu/g |
-E.Coli | Negative | Negative |
-Salmonella | Negative | Negative |
Conclusion | Comply with USP43. | |
Storage | Preserve in tight containers, protected from strong light and high heat. |
Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
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