Sugarcane Wax Extract Policosanol Octacosanol Powder

Basic Information:

Common Names: Octacosanol

Botanical Source: Sugarcane Wax
Chemical Name: 1-Octacosanol, n-Octacosanol
CAS No.: 557-61-9
Appearance: White Powder
Specification: Octacosanol 30% 50%, 60%, 90%

Melting Point: Approximately 81-83°C

Boiling Point: Approximately 437°C (at 760 mmHg)

Solubility: Insoluble in water; soluble in ethanol, chloroform, acetone, and other organic solvents

Pharmacology:

Mechanism of Action: Octacosanol is believed to exert its effects through various mechanisms, including:

Physical Endurance and Performance: Enhances exercise performance and endurance, possibly by improving the efficiency of muscle energy production.

Cholesterol-Lowering: May inhibit cholesterol synthesis and increase cholesterol excretion.

Antioxidant: Scavenges free radicals and reduces oxidative stress.

Function:

Enhances Stress Tolerance: Improves the body's ability to withstand stress.

Boosts Reactive Sensitivity: Increases responsiveness to various stimuli.

Improves Cardiac Function: Enhances the performance of the heart muscle.

Reduces Cholesterol and Blood Pressure: Lowers cholesterol levels, blood fat, and systolic pressure.

Increases Stamina and Vitality: Strengthens stamina, vigor, and overall physical strength.

Supports Hormone Function and Eases Muscle Pain: Promotes the function of sex hormones and helps alleviate muscle pain.

Application:

Cholesterol Management: Policosanol is a natural compound derived from sugar cane wax that helps lower cholesterol. It is considered safe and well-tolerated, even in people using multiple medications.

Lipid Profile Improvement: Policosanol has been shown to improve lipid profiles in various groups, including healthy individuals, people with type II hypercholesterolemia, type 2 diabetics with high cholesterol, postmenopausal women with high cholesterol, and individuals with both high cholesterol and liver function abnormalities. However, recent studies have raised some controversy regarding its efficacy.

Comparable to Statins: In clinical studies, Policosanol has performed as well as or better than statins such as simvastatin, pravastatin, and lovastatin, with fewer side effects, for patients with type II hypercholesterolemia.

Cardiovascular Health: Used to support heart and blood vessel health, including conditions like high cholesterol, leg pain from poor circulation (intermittent claudication), and narrowing of blood vessels.

Mechanism of Action: Policosanol appears to decrease cholesterol production in the liver and enhance the breakdown of LDL ("bad") cholesterol. It also reduces platelet stickiness, potentially lowering the risk of blood clots.