Basic Information:
Product Name: Tetrandrine
Chemical Information:
IUPAC Name: (1R,12S)-10,11-Dimethoxy-1,2,6,7-tetradehydro-1-(3,4,5-trimethoxybenzyl)tetrandrine
Molecular Formula: C38H42N2O6
Molecular Weight: 622.75 g/mol
CAS Number: 518-34-3
Physical Properties:
Appearance: White to off-white crystalline powder
Melting Point: Approximately 224-226°C
Solubility: Sparingly soluble in water; more soluble in ethanol, chloroform
Function:
Anti-inflammatory and Antiallergic: Exhibits strong anti-inflammatory, immunomodulatory, and antiallergenic effects by inhibiting the degranulation of mast cells.
Vasodilatory Effect: Dilates blood vessels, thereby lowering blood pressure and improving cardiovascular health.
Liver Health: Shows potential in the treatment of liver diseases, including liver cancer.
Anti-fibrotic Properties: May prevent excessive scarring and fibrosis, particularly in the conjunctiva following trabeculectomy, or in cases of severe conjunctival inflammation.
Broad Therapeutic Applications: Combines anti-inflammatory and antifibrogenic actions, making it potentially useful for treating conditions like lung silicosis, liver cirrhosis, and rheumatoid arthritis.
Application:
Food Industry: Utilized as a food additive, it contributes to longevity and overall health.
Health Supplements: Popularly used in health supplements and over-the-counter products for its benefits in treating cancer and cardiovascular diseases.
Cosmetics Industry: Incorporated into cosmetic products to delay aging and protect against UV radiation.
Additional Benefits
Liver Disease and Cancer Treatment: Promising in the treatment of liver disease and liver cancer, supporting liver health and reducing cancer risk.
Post-Surgical and Inflammatory Eye Treatment: Helps prevent scarring and fibrosis in the conjunctiva post-trabeculectomy and in patients with severe conjunctival inflammation.
Treatment for Chronic Conditions: Effective in the management of chronic conditions such as lung silicosis, liver cirrhosis, and rheumatoid arthritis due to its anti-inflammatory and antifibrotic properties.
Cosmetic Benefits: Offers anti-aging properties and UV protection when used in skincare formulations.
