Basic Information:
Product Name: Genistein
IUPAC Name: 5,7-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
Molecular Formula: C15H10O5
Molecular Weight: 270.24 g/mol
CAS Number: 446-72-0
Physical Properties:
Appearance: Off-white to yellow crystalline powder
Melting Point: Approximately 297-298°C
Solubility: Poorly soluble in water; soluble in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO)
Function:
Antioxidant Powerhouse: Genistein is a potent antioxidant that neutralizes harmful free radicals and reduces lipid peroxidation.
Cardiovascular Protection: Acts as an anticoagulant, preventing heart attacks and strokes by inhibiting blood clot formation.
Enzyme Activation: Boosts the activity of other antioxidant enzymes, including glutathione peroxidase, superoxide dismutase, and glutathione reductase.
Cell Growth Regulation: Influences the growth of cells, including those that are not hormone-dependent.
Tyrosine Kinase Inhibition: Inhibits the activity of tyrosine kinase, a crucial enzyme in cell growth.
Cancer Risk Reduction: Reduction in tyrosine kinase activity is associated with a lower risk of cancer.
Application:
Dietary Supplements: Available in capsule form for those who prefer supplementing their diet with isoflavones.
Menopausal Support: A daily supplement containing at least 54 mg of genistein is recommended for alleviating hot flashes in postmenopausal individuals.
IBS Management: A dosage of 40 mg of isoflavones per day for six weeks has been shown to help with symptoms of Irritable Bowel Syndrome (IBS).
Osteoporosis Protection: A daily supplement of 80 mg of soy isoflavones can help reduce bone loss and protect against osteoporosis in postmenopausal individuals.
General Use: No specific dosage is established for general supplementation, and the long-term safety of taking isoflavones beyond six months has not been guaranteed.
