Basic Information:
Product Name: Nobiletin
IUPAC Name:
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
Molecular Formula: C21H22O8
Molecular Weight: 402.39 g/mol
CAS Number: 478-01-3
Physical Properties:
Appearance: Light yellow crystalline powder
Melting Point: Approximately 132-136°C
Solubility: Poorly soluble in water; soluble in ethanol, methanol,
Function:
Vascular Health: Nobiletin dilates blood vessels, protects vascular endothelium, and prevents arteriospasm.
Blood Circulation Improvement: Inhibits platelet activating factor (PAF) and thrombosis, enhancing blood circulation.
Cardiac and Cerebral Support: By improving microcirculation and reducing free radical damage, it enhances the nutrition and metabolism of cardiac and cerebral cells, improving memory and treating post-stroke sequelae.
Cholesterol Reduction: Helps lower cholesterol levels, contributing to overall cardiovascular health.
Digestive Aid: Enhances intestinal motility, promoting better digestion.
Cognitive and Acne Improvement: Some studies suggest it may improve memory impairment and treat acne.
Anti-Tumor Properties: Exhibits anti-tumor activities, suppressing the proliferation of cancer cells.
Application:
Food Industry: Used as an ingredient in various food products.
Nutritional Supplements: Formulated into tablets or capsules, often used to alleviate symptoms such as reduced appetite and excessive sputum production.
Cosmetics: Included in many skincare products, particularly those using orange peel oil, to nourish and rejuvenate the skin.
Anti-Aging Skincare Products: Nobiletin is increasingly incorporated into anti-aging creams, serums, and lotions due to its powerful antioxidant properties. By neutralizing free radicals, it helps reduce fine lines, wrinkles, and signs of photoaging, making it a popular ingredient in age-defying skincare formulas.
Acne and Inflammation Relief: Thanks to its anti-inflammatory and sebum-regulating effects, Nobiletin is used in acne treatments and soothing gels to calm irritated skin, reduce redness, and prevent breakouts. It is especially beneficial for oily and combination skin types.
Skin Brightening and Tone Improvement: Nobiletin inhibits tyrosinase activity, making it effective in skin-brightening and pigmentation-correcting products. It helps reduce dark spots, even out skin tone, and restore a natural glow, making it ideal for whitening serums and dark spot correctors.
Natural Health Supplements for Skin & Wellness: When formulated as a nutraceutical, Nobiletin supports overall skin vitality from within. It boosts microcirculation, improves nutrient delivery to skin cells, and helps the skin recover from stress and environmental damage, promoting a healthy complexion.
Post-Treatment Recovery Support: Its vascular-protective and anti-inflammatory functions make Nobiletin suitable for post-laser or post-acne recovery creams, enhancing tissue repair and reducing inflammation after cosmetic procedures.
Stress-Related Skin Condition Alleviation: Due to its ability to enhance cognitive health and circulation, Nobiletin also indirectly benefits individuals suffering from stress-related skin issues such as dullness, sensitivity, or flare-ups, offering mind-skin axis support.
