Basic Information:
Common Names: Apigenin
Specs:1-98% HPLC
Molecular Formula: C15H10O5
Molecular Weight: 270.24 g/mol
CAS Number: 520-36-5
Appearance: Yellow crystalline powder
Melting Point: Approximately 345°C (dec)
Solubility: Poorly soluble in water; more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO)
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Function:
Anti-Inflammatory Effects: Apigenin exerts anti-inflammatory actions by inhibiting NO synthase and COX2 enzymes in macrophages, thus reducing the influence of lipopolysaccharides. It also inhibits interleukin-4 production and TNFα elevation by interfering with NF-kB transcription and potential TNFα-induced upregulation of adhesion molecules.
Soothing and Relaxation: Promotes relaxation and helps soothe at bedtime.
Childhood Relief: Relieves restlessness, teething discomfort, and colic in children.
Antihistamine Properties: Acts like an antihistamine to alleviate allergies.
Digestive Aid: Facilitates digestion when consumed as a tea after meals.
Morning Sickness Relief: Eases morning sickness during pregnancy.
Skin Healing: Accelerates healing of skin ulcers, wounds, and burns.
Gastritis and Colitis Treatment: Treats gastritis and ulcerative colitis.
Antibacterial Effects: Chamomile extract, rich in flavonoids, possesses significant antibacterial properties.
Sunscreen and Emollient: Provides sunscreen effects and moisturizes the skin.
Application:
Cancer Treatment: Apigenin is a potent anticancer compound, highly selective for cancer cells, inducing apoptosis without harming normal cells. It can be integrated into a diet rich in fruits and vegetables for its active doses.
Food Industry: At 98%, apigenin is used as a nutrient-rich food additive.
Cosmetics: At 98%, apigenin is formulated into cosmetic products for its whitening, anti-wrinkle, and UV-protection properties.
Apigenin, derived from chamomile extract, offers a broad spectrum of therapeutic benefits. It acts as a powerful anti-inflammatory agent, a soothing and relaxing compound, a digestive aid, and a skin healer. Its potent anticancer properties, combined with its versatility across food and cosmetic industries, highlight its significant role in both health and wellness applications.
